They’re very different animals. The series basically takes the books as a setting and a very general overall story structure, along with a few key characters, and the rest is spinning out very differently. And that’s okay, because trying to do a 1:1 translation to the screen would not work at all.

Asimov was more interested in the big ideas than he was in the emotional lives of the characters, and this show is conversely more invested in the ways these situations affect its characters than to spending too much time on the big crazy sci-fi concepts which serve as its backdrop.