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Joined 1 year ago
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Cake day: June 27th, 2023

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  • GTFO with that “politics” bullshit. It stopped being a purely political difference when Trump made it about racism, sexism, and all other possible forms of bigotry. It stopped being about purely bigotry when he tried to stage a coup.

    Above and beyond, you don’t know their life. Maybe they needed a life-saving abortion and their father gleefully cackled when that right was effectively removed in many states. Maybe they’re black and their father bragged about the shootings of black folks, they’re latin and he chortled over the deportation rhetoric, or they’re Muslim and he rubbed the travel bans in their face. Maybe they have/had long COVID and their father gave it to them because “it’s a hoax.” There are so many reasons for cutting MAGA idiots out of your life and Trump’s political policy is the least of them


  • niucllos@lemm.eetoScience Memes@mander.xyz...
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    12 days ago

    Sure, there will be examples of problems in any field that has hundreds of thousands to millions of humans working in it. That doesn’t mean there’s a broad crisis, and it doesn’t mean that most research is faked or fallible. In your 2004 example, all of the data wasn’t faked, some images for publication were doctored. There’s been potential links between alzheimer’s and aBeta amyloids since at least 1991 (1), long before this paper that posited a specific aB variant as a causal target. Additionally, other Alzheimer’s causes and treatments are also under investigation, including gut microbiome studies since at leasg 2017 (2). Finally, drugs targeting aB proteins to remove brain plaques work in preclinical trials, indicating that the 2004 paper was at least on the right track even if they cheated to get their paper published. This showcases science working well: bad-faith actors behaved unethically, but the core parts of their work were replicated and found to be effective, so some groups followed that to clinical trials which are still ongoing, and others followed other leads for a more holistic understanding of the disease.

    Also, I’d very much argue that human neurological diseases are both bleeding edge and niche, which inherently means that recognizing problems in studies will take more time than something that is cheaper or faster to test and validate, but problems will eventually be recognized as this one was.

    1. Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proc Natl Acad Sci USA. 1991;88:7552–6.
    2. Cattaneo, A. et al. Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly. Neurobiol. Aging 49, 60–68 (2017).

  • niucllos@lemm.eetoScience Memes@mander.xyz...
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    13 days ago

    I wouldn’t call it a broad crisis, and it isn’t universal. More theoretical sciences or social sciences are more prone to it because the experiments are more expensive and you can’t really control the environment the way you can with e.g. mice or specific chemicals. But most biology, chemistry, etc that isn’t bleeding edge or incredibly niche will be validated dozens to hundreds of times as people build on the work and true retractions are rare



  • I’m not saying me driving an EV does statistically anything to reduce carbon emissions, or even that if I got all my friends and family to go vegan and bike instead of drive cars that it would. I am saying that the broad public doesn’t care about these issues enough to consume differently or vote for policy or politicians that make their lives less convenient in order to fight climate change, and that instead our individual actions to avert climate change contribute to a public ethos that can accept lifestyle changes and that may potentially hold the mega polluting corporations to account and fix our throw-away durable goods culture in a way that media-demonized protests and pestering bought-and-paid politicians never can.


  • While this is basically true, what it ignores is the impact personal decisions make on the ethos around us to build support for legal pressure. I have family that doesn’t disbelieve climate change but isn’t motivated by it, and by us going mostly meatless and buying and EV they’ve started meatless Mondays and Thursdays and are considering an EV for their next car. Our individual actions ripple out, and create a public normalization for these types of changes so that it isnt an uphill battle to get uninformed laypeople to care about climate policy at the polling stations





  • I’m going to be a bit blunt, but unfortunately you didn’t score big in a cash sense. The tag on the arm is to make it easier to check brand on a store rack and is designed to be easily cut off–having it still on does increase its value as it’s a sign of low/no use. However, tailored clothing like suits and blazers are a relatively niche and very saturated market, so unless it’s a new or like-new 100% wool or wool/silk blend in the classic 2-button style and from a very well known brand (Brooks Brothers, Hugo Boss, etc.), it’s going to be very hard to sell it for much because people can just do what you did and go to a thrift store and choose from tons of suits for ~$8 each. Even if the store originally charged $800 for it, as another poster commented these suits are selling for ~$30-$100 on Poshmark and most of those listings have been up for months. If you’re very patient you could maybe get $20-$50.

    However, if it fits well and you like it, you scored a fantastic clothing deal on a fun jacket, so congratulations! The money you saved instead of buying the $300 jacket at DXL is now free for your emergency fund!



  • niucllos@lemm.eetoAndroid@lemmy.worldFond memories
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    2 months ago

    Gesture typing is definitely faster, but I find it much less accurate and requires vision. My old sliding phone I could write whole essays in my hoodie pocket while walking home with few to no typos, which was a niche use-case for sure but an existing one. I work outside a fair amount and would love having that back for notetaking in the field




  • This premise gets thrown around a lot but I actually disagree. “Every time people turn out” is always also thrown in there like some arbitrary thing–when I think the past several election cycles have shown that when there are younger, more progress candidates who make it past the primaries turnout shoots up. Courting the 3% uninformed flip-floppers by moving right is a losing strategy when you could be motivating your own party to turn out by moving left and driving turnout up. There’s no money in that though, so dumb centrists get wooed


  • What you’re describing definitely sounds like a fountain pen–specifically, an eyedropper (where the body acts as the ink reservoir), desk (long, gently sloping body coming to a point) pen–did it look something like this? https://cdn11.bigcommerce.com/s-5ko0zosub2/product_images/description/sheaffer/sh_deskpen_greymarble_2.jpg (Sorry, can’t get images to embed)

    For your thinish line requirements with a non-scratchy nib, I’d suggest a European/American fine or Japanese medium nib size (Japanese brands tend to run thinner). Most pens you can buy have some sort of cartridge, as well as a converter that would allow you to use a bottle–you can also get a cheap blunt tipped syringe or pipet and refill washed cartridges with whatever ink you want. I use a hot glue gun to reseal mine for transport, and peel it off before reinserting the cartridge.

    I would recommend going to a stationary store/office supply store and trying some out! If you give us a general geographic area we can try to recommend stores near you that cary pens you could try–in Europe I’ve found this much more common than the US. If in-person testing isn’t an option, I would tentatively suggest a pilot kakuno–they look like they cost ~11€ in Europe, and come with one cartridge of ink. They’re Japanese so I would recommend a medium if you want to avoid scratchy at all costs, or a fine if you have some tolerance for a bit of feedback and want a thinner line. Any of pilot’s converters should work, looks like they cost ~6-12€ depending on refill mechanism and capacity.

    A kakuno or other budget pen won’t look as amazing, but in my experience write almost as well as pens costing 10x more, and honestly if it’s your first one you probably won’t be able to feel the nuance yet.



  • niucllos@lemm.eetoTechnology@lemmy.world*Permanently Deleted*
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    2 months ago

    Look, I’m with you most of the way in theory, but a lot of rural areas don’t have plumbing and drinking water from public utilities, they have their own septic and water wells. I know it’s pedantic but a lot of parts of the world are so rural that it probably doesn’t make sense to have fully public transport, like it doesn’t make sense to have centralized water. The scope needs to be great systems within towns and cities and lots of park and ride hubs around the perimeter