Ibuprofen is mostly processed by your liver as well. Acetaminophen uses a bit of both.
This appears to occur predominantly systemically in the liver [1,10], but may occur pre-systemically in the gut as well [11]. Ibuprofen is almost completely metabolized, with little to no unchanged drug found in the urine [1,9,12].
Tylenol (acetaminophen) is almost completely broken down by the liver. During this process, a toxic chemical forms. Normally, the liver makes it non-toxic. But if you take too much Tylenol, the liver can’t properly process it all. The toxic chemical can then build up and poison liver cells.
Was he on narcotics? I’m finding no link between Acetaminophen or Ibuprofen to kidney stones. Just drink more water.
https://www.utsouthwestern.edu/newsroom/articles/year-2023/june-prevent-kidney-stones.html
https://pubmed.ncbi.nlm.nih.gov/30829133/
Ibuprofen is mostly processed by your liver as well. Acetaminophen uses a bit of both.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/
https://www.goodrx.com/acetaminophen/is-tylenol-acetaminophen-bad-for-your-liver-or-kidneys
https://pubmed.ncbi.nlm.nih.gov/8669426/
https://www.goodrx.com/acetaminophen/is-tylenol-acetaminophen-bad-for-your-liver-or-kidneys